To systematically analyze factors influencing fertility concerns among cancer patients to inform clinical practice, particularly regarding early intervention strategies.
Key Findings:
Depression (OR = 1.30, 95%CI = 1.14-1.49) is associated with increased fertility concerns.
Having more than one child (OR = 0.32, 95%CI = 0.23-0.41) reduces anxiety.
Being married (OR = 0.44, 95%CI = 0.26-0.75) is linked to lower fertility concerns.
Full-time employment (OR = 1.41, 95%CI = 1.03-1.93) is associated with increased anxiety.
Endocrine therapy (OR = 1.31, 95%CI = 1.07-1.62) and reproductive counseling (OR = 1.21, 95%CI=1.01-1.45) are significant factors.
Interpretation:
Endocrine therapy and prior fertility counseling are significantly associated with elevated fertility concerns, indicating a complex interplay between medical interventions and psychological distress, with implications for clinical practice.
Limitations:
Variations in sample sizes and regional focus may affect generalizability, potentially limiting the applicability of findings.
Limited research on fertility concerns in China indicates a need for more targeted studies to address this gap.
Conclusion:
This study highlights the importance of addressing fertility concerns in cancer patients, emphasizing the need for early discussions about infertility risks and preservation options to improve patient outcomes.
