To report a case of primary solitary gastric plasmacytoma and review its clinical features, diagnostic approaches, therapeutic strategies, and prognosis.
Approach:
Case Presentation: A 53-year-old male presented with persistent acid reflux and heartburn. Gastroscopy identified a flat, elevated lesion in the gastric body, leading to endoscopic mucosal resection.
Diagnostic Assessment: Histopathology and immunohistochemistry confirmed the diagnosis of primary solitary gastric plasmacytoma, with exclusion of multiple myeloma through various tests.
Key Findings:
Gastric plasmacytoma is a rare subtype of extramedullary plasmacytoma, accounting for about 2% of cases.
The patient presented with nonspecific gastrointestinal symptoms and was initially misdiagnosed with chronic gastritis.
Histopathological examination revealed diffuse infiltration of monoclonal plasma cells, confirming the diagnosis.
The diagnosis was confirmed through histopathology, immunohistochemistry, and exclusion of multiple myeloma via various tests.
Interpretation:
This case emphasizes the need to consider gastric plasmacytoma in patients presenting with atypical gastric lesions and nonspecific gastrointestinal symptoms.
Limitations:
Lack of large-scale clinical studies on primary gastric plasmacytoma limits understanding of its etiology and prognosis.
The rarity of the condition may lead to misdiagnosis or delayed diagnosis, impacting patient outcomes.
Conclusion:
This case report aims to enhance clinical awareness of gastric plasmacytoma and highlights the importance of thorough diagnostic evaluation.
