Frequency and characteristics of transfusion-transmitted infections in blood donors at a tertiary care facility in Pakistan - Summary - MDSpire

Frequency and characteristics of transfusion-transmitted infections in blood donors at a tertiary care facility in Pakistan

  • By

  • Komal Iqbal

  • Sadia Farhad

  • Malik Shayan Ali Khan

  • Muhammad Hassan Jan

  • Inbasat Zahra Khan

  • Muhammad Umair

  • Bilal Hassan

  • Rafiullah Hotak

  • March 9, 2026

  • 0 min

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Objective:

To assess the prevalence and demographic distribution of transfusion-transmitted infections (TTIs) among blood donors at MMC-MTI Mardan, Pakistan, highlighting its significance for public health.

Key Findings:
  • Overall TTI prevalence in Pakistan is 4.61%, with replacement donors at 5.42%, indicating a critical public health concern.
  • Only 10%-13% of blood donations are voluntary, underscoring the need for improved donor recruitment strategies.
  • TTIs are more prevalent among male donors and those aged 25-44 years, suggesting targeted interventions for these demographics.
Interpretation:

The high prevalence of TTIs, particularly among replacement donors, indicates systemic issues in blood donation practices and highlights the urgent need for improved voluntary donation initiatives and screening protocols.

Limitations:
  • Lack of updated data on TTIs in smaller cities, which may lead to underrepresentation of the issue.
  • Weak surveillance systems hinder evidence-based policy-making and may introduce biases in data collection.
Conclusion:

The study provides critical insights into the prevalence of TTIs in Pakistan, emphasizing the urgent need for enhanced donor screening and promotion of voluntary blood donation to improve transfusion safety.

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