Characterizing Musculoskeletal Sequelae in Ebola Virus Survivors During the 7 Years Since Hospital Discharge in Eastern Sierra Leone - Summary - MDSpire

Characterizing Musculoskeletal Sequelae in Ebola Virus Survivors During the 7 Years Since Hospital Discharge in Eastern Sierra Leone

  • By

  • Anna C Sanford

  • Nell G Bond

  • Emily J Engel

  • Foday Alhasan

  • Michael Gbakie

  • Fatima Kamara

  • Lansana Kanneh

  • Ibrahim Mustapha

  • Mohamed Yillah

  • Donald Grant

  • Robert Samuels

  • John S Schieffelin

  • March 8, 2025

  • 0 min

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Objective:

To analyze musculoskeletal (MSK) signs and symptoms in Ebola virus disease (EVD) survivors over a 7-year period post-discharge, highlighting the long-term impact on health.

Key Findings:
  • 38.9% of survivors reported current MSK symptoms at enrollment, with fluctuations noted over time.
  • Joint pain and tenderness were the most common sequelae.
  • Survivors aged 15-40 years exhibited the highest rates of MSK sequelae.
  • MSK symptoms generally decreased over time, but fluctuations were observed, indicating variability in recovery.
Interpretation:

EVD survivors experience significant long-term MSK complications, particularly in younger adults, indicating a need for targeted treatment, monitoring, and healthcare policy adjustments.

Limitations:
  • Follow-up data was limited for some survivors, potentially affecting the comprehensiveness of findings.
  • Potential biases in self-reported symptoms may influence the accuracy of the data.
  • The geographical focus on Sierra Leone may limit the generalizability of the findings to other regions.
Conclusion:

Musculoskeletal sequelae are prevalent among EVD survivors, necessitating ongoing assessment and management strategies, including targeted rehabilitation programs.

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