Shallow Acupuncture for brainstem infarction: a randomized controlled trial protocol - Summary - MDSpire

Shallow Acupuncture for brainstem infarction: a randomized controlled trial protocol

  • By

  • Hongge Zuo

  • Yan Huang

  • Weikang Huang

  • Jiahui Lin

  • Jinyuan Fang

  • Zhenhua Xu

  • July 10, 2026

  • 0 min

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Objective:

To evaluate whether adjunctive Shallow Acupuncture improves activities of daily living in patients with brainstem infarction and to examine associated neural changes.

Approach:
  • Trial Design: Single-center, randomized, assessor- and statistician-blinded, pragmatic add-on controlled trial.
  • Participants: 62 patients with brainstem infarction randomly assigned to either a conventional acupuncture group or an adjunctive Shallow Acupuncture group.
  • Intervention: Both groups receive standard medical management, routine rehabilitation, and conventional acupuncture; the adjunctive group receives Shallow Acupuncture daily for 14 days.
  • Outcome Measures: Primary outcome: activities of daily living assessed by the Barthel Index. Secondary outcomes: NIH Stroke Scale and modified Rankin Scale. Exploratory indicators: rs-fMRI and DTI measures.
  • Assessment Timing: Clinical outcomes assessed at baseline, post-treatment, and 1-month follow-up; neuroimaging at baseline and post-treatment.
Key Findings:
  • Brainstem infarction is a significant contributor to stroke-related morbidity and mortality.
  • Current management strategies for brainstem infarction are limited and often do not focus on functional recovery.
  • Acupuncture is recommended in Chinese guidelines as an adjunctive therapy for acute ischemic stroke.
Interpretation:

Limitations:
  • Single-center study may limit generalizability.
  • Sample size of 62 may not capture the full variability of outcomes.
Conclusion:

This trial aims to provide evidence on the effectiveness of Shallow Acupuncture in improving functional recovery in patients with brainstem infarction.

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