To evaluate the association of SIRI and NLPR at admission with hospital-acquired post-operative pneumonia in middle-aged and elderly patients after hip fracture surgery.
Approach:
Study Design: A retrospective study involving 452 patients aged 45 years or older who underwent hip fracture surgery.
Data Collection: SIRI and NLPR were calculated based on peripheral blood cell counts measured at admission.
Group Division: Patients were divided into a pneumonia group (n = 25) and a non-pneumonia group (n = 427) based on the occurrence of hospital-acquired post-operative pneumonia.
Statistical Analysis: Multivariable logistic regression analysis and ROC curve analysis were employed to evaluate associations and performance of SIRI and NLPR.
Key Findings:
5.53% of patients developed post-operative pneumonia.
Both SIRI and NLPR showed a positive association with the risk of pneumonia after hip fracture surgery.
SIRI and NLPR demonstrated moderate discriminative performance (AUC: 0.701 and 0.738, respectively).
An elevated NLPR above the optimal cut-off value of 2.879 was significantly associated with an increased incidence of POP (OR = 5.47, 95% CI: 1.95–20.8).
Interpretation:
Both SIRI and NLPR are associated with the occurrence of hospital-acquired post-operative pneumonia in middle-aged and elderly patients with hip fracture.
Limitations:
The study is retrospective and may have inherent biases.
The clinical utility of SIRI and NLPR as early warning indicators requires further external validation.
Conclusion:
SIRI and NLPR may serve as auxiliary screening tools for ruling out post-operative pneumonia in low-risk patients.
