To determine the prevalence of symptomatic pleural effusion among liver transplant candidates, compare demographic and disease-severity characteristics, and examine the association of pre-transplant pleural effusion with post-transplant mortality (30-day, 90-day, and overall).
Approach:
Key Findings:
12.8% of liver transplant candidates had symptomatic pleural effusion, with statistical significance.
Patients with pleural effusion exhibited higher MELD and Child-Pugh scores.
Pre-transplant pleural effusion was associated with increased short-term mortality post-transplant.
Interpretation:
Symptomatic pleural effusion in liver transplant candidates indicates more severe liver disease and correlates with worse post-transplant outcomes, highlighting the need for careful evaluation in candidate selection.
Limitations:
Retrospective design may introduce selection bias.
Single-center study limits generalizability.
Potential confounding factors affecting results were not controlled.
Conclusion:
Symptomatic pleural effusion is prevalent among liver transplant candidates and is linked to higher mortality rates post-transplant, suggesting the need for careful consideration in candidate evaluation.
The number of liver transplants performed in the United States is higher than it’s ever been. For patients in need, including those with end-stage liver disease, acute liver failure or liver cancer, it’s life-saving news.