To evaluate the integration of long-acting antiretroviral therapy (LA-ART) at the Maria X. Martinez Health Resource Center for individuals experiencing homelessness from November 2021 to October 2025.
Approach:
Patient Population: The study included patients receiving LA-ART from November 2021 to October 2025 and those with 2 or more medical visits between January 2023 and December 2024.
Key Findings:
The MXM Health Resource Center served 4424 adults experiencing homelessness in the 2023-2024 fiscal year.
Patients included 66% cisgender men, 30% cisgender women, and 3% transgender or nonbinary individuals.
28% identified as Black, 18% as Hispanic or Latine, and 52% as White.
Interpretation:
The study highlights the potential for LA-ART to be effectively integrated into community-based settings for individuals facing significant barriers to traditional HIV care.
Limitations:
The study was exempt from IRB review, limiting the depth of ethical oversight.
Data were collected retrospectively, which may affect the reliability of outcomes.
Conclusion:
The integration of LA-ART in community-based clinics may improve access to HIV treatment for individuals experiencing homelessness.
by Nicky J. Mehtani, Stephen J. Matzat, Kathleen B. O’Connor, Laura Cordoba, Sarah Strieff, Alix Strough, Morgan M. Philbin, Mallory O. Johnson, Monica Gandhi, Barry Zevin
Updated 2025-2026 vaccination was linked to added protection in a CDC-funded analysis that became part of a broader debate over routine vaccine monitoring.
