To develop a conceptual framework describing associations between water-energy-food (WEF) insecurities and health outcomes in South Africa.
Approach:
Study Design: A scoping review combined with expert consultations was conducted to inform framework development.
Framework Development: The framework was designed to connect resource systems and human well-being, identifying integrated, cross-sectoral interventions.
Key Findings:
Approximately 2.11 million people in South Africa lack access to safe water.
3.5 million households rely on biomass for cooking or heating.
An estimated 14 million people experience food insecurity.
Interpretation:
The study highlights the need for systematic mapping of how WEF insecurities interact to produce health effects, emphasizing the complexity of these interconnections.
Limitations:
Limited systematic mapping of WEF insecurities and health interactions in existing literature.
Health is often only partially integrated in studies focusing on single WEF components.
Conclusion:
The framework aims to provide a foundation for understanding the interconnected risks posed by WEF insecurities and their impact on health.
A posthoc analysis of a phase 2b trial found favorable changes in DNA methylation–based aging biomarkers among patients with human immunodeficiency virus–associated lipohypertrophy.
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