Vitamin D status and Its association with haematological inflammatory indices and cardiometabolic risk profiles: a retrospective cross-sectional study - Summary - MDSpire
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Vitamin D status and Its association with haematological inflammatory indices and cardiometabolic risk profiles: a retrospective cross-sectional study
To evaluate the associations of vitamin D status with specific haematological inflammatory indices (NLR, PLR, MLR, SII) and cardiometabolic risk markers (lipid and glycemic parameters) in adults.
Approach:
Key Findings:
Vitamin D deficiency was associated with adverse inflammatory and cardiometabolic profiles, indicating a significant relationship.
Low vitamin D status coexisted with less favorable inflammatory and metabolic profiles, suggesting a potential area for intervention.
NLR, PLR, and SII were consistent markers but had modest discriminatory performance, limiting their standalone diagnostic use.
Interpretation:
Vitamin D status may influence the relationships between haematological inflammatory indices and cardiometabolic risk markers, potentially guiding clinical assessments.
Limitations:
Retrospective design limits causal inferences, and the study may not account for all potential confounding factors such as lifestyle and dietary habits.
Conclusion:
The study suggests a relationship between vitamin D levels and inflammatory indices in the context of cardiometabolic risk.
by Yaqeen Mohammed Al-Essa, Hussain Khalifa Aljumah, Zainab Younis Al saeed, Raneem Abdullah AlQattan, Danah Yousef Alquwayzani, Ghadeer kazem Al-Yousef, Ayah Salem AL owdah, Mujtaba Abbas Alzuwayr, Eman Elsheikh
In a pooled analysis of more than 1.5 million patients, sugar-sweetened beverages were associated with higher risks of HCC and ICC, while artificially-sweetened beverages showed no independent association with hepatic cancer.
