What Changes Under 2025 ASE Diastolic Function Criteria? - Summary - MDSpire
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What Changes Under 2025 ASE Diastolic Function Criteria?
Researchers applied the 2016 and 2025 American Society of Echocardiography diastolic function guidelines to 87,724 echocardiograms that met criteria for analysis.
To evaluate the impact of the 2025 American Society of Echocardiography diastolic function grading guidelines compared to the 2016 guidelines.
Approach:
Study Design: A retrospective, single-center cohort study analyzing 300,828 adult transthoracic echocardiograms performed between 2013 and 2022.
Data Analysis: Both 2016 and 2025 diastolic function grading algorithms were applied to echocardiograms, with a total of 87,724 studies meeting criteria for analysis.
Statistical Modeling: A multiple logistic regression model was created to predict upgraded diastolic dysfunction based on demographic and clinical characteristics.
Key Findings:
20.1% of echocardiograms received different diastolic function grades under the 2025 guidelines.
14.0% of studies were upgraded, 6.1% were downgraded, and 79.9% remained unchanged.
The proportion of studies classified as having normal diastolic function decreased from 78.9% (2016) to 73.8% (2025).
Grade 1 diastolic dysfunction increased from 11.9% to 15.7%, Grade 2 from 6.4% to 8.4%, while Grade 3 decreased from 2.7% to 2.0% under the new guidelines.
Older age, female sex, and higher left ventricular systolic function were associated with increased diastolic dysfunction grading using the 2025 guidelines.
Interpretation:
More studies were classified as having diastolic dysfunction under the 2025 guidelines compared to the 2016 guidelines.
Limitations:
The study was conducted at a single center, which may limit generalizability.
Disclosures were not reported in the supplied abstract text.
Conclusion:
The 2025 guidelines result in a higher classification of diastolic dysfunction compared to the 2016 guidelines.
