Global, regional and national burden of polycystic ovary syndrome: historical trends from 1990 to 2021 and projections to 2035 - Summary - MDSpire

Global, regional and national burden of polycystic ovary syndrome: historical trends from 1990 to 2021 and projections to 2035

  • By

  • Hu Li

  • Zhaoyi Jing

  • Rui Li

  • Zheng Shen

  • Tianyu Bai

  • Qingyu Song

  • April 1, 2026

  • 0 min

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Objective:

To deepen the understanding and assessment of the global burden of polycystic ovary syndrome (PCOS) for policy-making and resource allocation, particularly in achieving specific global health goals.

Key Findings:
  • The burden of PCOS is increasing, particularly among the 10–19 age group, with the majority of cases in the 15–49 age group, indicating a need for targeted interventions.
  • Countries with a higher Socio-demographic Index (SDI) bear a heavier burden of PCOS, suggesting a correlation between economic status and health outcomes.
  • Population growth and epidemiological changes are significant drivers of the increasing burden of PCOS, necessitating urgent public health responses.
  • By 2035, the burden of PCOS is projected to continue increasing, highlighting the need for proactive measures.
Interpretation:

The global burden of PCOS is rising, with notable regional and national disparities, indicating a need for targeted interventions and support, especially in low SDI countries, to address these inequities.

Limitations:
  • Underdiagnosis of PCOS, particularly in low SDI regions, may lead to an underestimation of its true burden, complicating public health responses.
  • Complexity in diagnosing PCOS can result in delays and inaccuracies in data collection, further skewing the understanding of its prevalence.
Conclusion:

The study highlights the increasing global burden of PCOS and the need for improved diagnostic criteria, public health awareness, and resource allocation to protect women's health, particularly in underserved regions.

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