Construction and verification of a prediction model for sleep disorders in older patients with coronary heart disease based on machine learning algorithms - Summary - MDSpire

Construction and verification of a prediction model for sleep disorders in older patients with coronary heart disease based on machine learning algorithms

  • By

  • Dali Dong

  • Xiang Peng

  • Siling Tan

  • Hua He

  • June 30, 2026

  • 0 min

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Objective:

To construct and validate a predictive model for sleep disorders in older adults with coronary heart disease (CHD) using machine learning algorithms.

Approach:
  • Study Design: A cross-sectional survey design was employed to collect clinical data from 338 older adult patients with CHD.
  • Data Collection: Participants were divided into two groups based on the presence of sleep disorders, and data were collected from questionnaires and electronic medical records.
  • Model Development: LASSO regression was used to screen risk factors, and Logistic regression, random forest (RF), and gradient boosting machine (GBM) models were built.
  • Model Evaluation: Receiver operating characteristic (ROC) and calibration curves evaluated model performance, with a temporal validation cohort of 152 older CHD patients.
Key Findings:
  • 24.26% of patients had sleep disorders, with 58 (24.07%) in the training group.
  • LASSO identified five risk factors: sex, duration of CHD, chronic gastritis, anxiety, and depression.
  • The RF model achieved the highest AUC (0.839) and accuracy (0.766) in the training set.
  • In the validation set, the GBM model achieved the highest AUC (0.838) and accuracy (0.733).
  • The Logistic regression model demonstrated the best specificity (0.875) and F1 score (0.825).
Interpretation:

The Logistic regression, GBM, and RF models based on identified risk factors demonstrated good predictive performance for sleep disorders in older adults with CHD.

Limitations:
  • The study was conducted in a single hospital, which may limit generalizability.
  • The sample size for the validation cohort was relatively small.
Conclusion:

The study provides a scientific basis for the early identification of sleep disorder risk and targeted intervention in older patients with CHD.

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