Hot flashes: a review - Summary - MDSpire

Hot flashes: a review

  • By

  • Sofia Jamal

  • Amira Elsabagh

  • Lubna Wani

  • Mayada Issa

  • June 25, 2026

  • 0 min

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Objective:

To summarize the clinical presentation, underlying pathophysiology, and current management of hot flashes.

Approach:
  • Clinical Presentation: Hot flashes are characterized by a transient sensation of internal heat, flushing, and sweating, affecting over 75% of women during menopause. Symptoms may significantly affect sleep quality.
  • Management Strategies: Management includes lifestyle modifications, complementary therapies with variable evidence, hormone replacement therapy for appropriate candidates, and nonhormonal pharmacologic approaches.
Key Findings:
  • Hot flashes significantly impair quality of life and are a common reason for seeking medical care.
  • Symptoms may occur in men, particularly those undergoing androgen deprivation therapy.
  • Frequent vasomotor symptoms may be associated with increased cardiovascular and cognitive risks, though causality remains unclear.
Interpretation:

Hot flashes are not life-threatening but can substantially affect daily functioning and quality of life.

Limitations:
  • Causality between hot flashes and long-term health outcomes remains unclear.
  • Variability in symptom presentation and management effectiveness among individuals.
Conclusion:

Effective recognition and management of hot flashes are crucial in outpatient care.

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