Primary orbital solitary fibrous tumor with an 18-year course of five recurrences and extensive sinonasal metastasis following eyeball enucleation: a case report - Summary - MDSpire
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Primary orbital solitary fibrous tumor with an 18-year course of five recurrences and extensive sinonasal metastasis following eyeball enucleation: a case report
To characterize the long-term clinical trajectory and management strategies for highly recurrent orbital solitary fibrous tumors (OSFT), highlighting the significance of these findings in the context of existing literature.
Key Findings:
The patient experienced five recurrences over 18 years, with increasing cellular atypia and mitotic activity in later recurrences, indicating a more aggressive tumor behavior.
Histopathological analysis confirmed the diagnosis of solitary fibrous tumor with nuclear STAT6 positivity.
The case highlights the aggressive potential of recurrent OSFT and the challenges in achieving complete resection, particularly in the context of extensive local invasion.
Limitations:
The study is based on a single case report, limiting generalizability and introducing potential biases.
Long-term outcomes and effectiveness of proposed management strategies are not established.
Conclusion:
Early complete surgical excision and integration of adjuvant radiotherapy are advocated for high-risk cases, along with lifelong surveillance, emphasizing the need for a multidisciplinary approach in management.
