Intrapericardial Triamcinolone Instillation for Recurrent Pericardial Effusion in Pediatric Patients: A Review of Efficacy and Safety - Summary - MDSpire

Intrapericardial Triamcinolone Instillation for Recurrent Pericardial Effusion in Pediatric Patients: A Review of Efficacy and Safety

  • By

  • Abhiram Reddy

  • Daniel Peck

  • Daniel Cortez

  • Bibhuti Das

  • John Bass

  • Varun Aggarwal

  • May 27, 2026

  • 0 min

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Objective:

To understand the use of intrapericardial triamcinolone in children with recurrent idiopathic pericardial effusion.

Approach:
    Key Findings:
    • Nine pediatric patients underwent intrapericardial triamcinolone administration.
    • Cytological, microbiological, and inflammatory marker testing of pericardial fluid showed elevated protein and LDH levels; all cultures and PCR tests were negative.
    • Median age at treatment was 21.5 months, with a range from 2 months to 16 years.
    • Duration of clinical stability post-triamcinolone varied, with a median time of 22.5 days between initial effusion drainage and treatment.
    Interpretation:

    Limitations:
    • Retrospective design may introduce bias.
    • Small sample size limits generalizability.
    • Lack of standardized echocardiographic measurement criteria.
    Conclusion:

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