To analyze infectious complications after transrectal systematic biopsy (SB) and MRI-targeted biopsy (MRI-TB) within 30 days of the procedure.
Key Findings:
Blood culture positive infections were rare, with 0.9% in both SB and MRI-TB cohorts.
Positive urine cultures were significantly lower in MRI-TB (1.7%) compared to SB (2.7%).
Elevated leukocytes were found in 2.5% after MRI-TB versus 3.9% after SB.
Elevated CRP levels were observed in 3.0% after MRI-TB compared to 4.2% after SB.
Signs and symptoms of infections were more common after SB than MRI-TB.
Interpretation:
While blood culture positive infections did not differ significantly between the two biopsy methods, other infectious complications were more prevalent after SB, suggesting a potential advantage of MRI-TB in reducing infection rates.
Limitations:
The study's retrospective nature may introduce bias.
The low number of blood culture positive infections limited statistical power.
The findings may not be generalizable to all clinical settings.
Conclusion:
MRI-targeted biopsy may be associated with lower rates of infectious complications compared to systematic biopsy, warranting further investigation in larger randomized trials.
