Prevalence of thyroid disorders in inland and coastal populations: A systematic review - Summary - MDSpire

Thyroid Disorder Incidence Among Coastal and Inland Populations: A Systematic Review

  • By

  • Samyuktha Thakadiyil Harikrishnan

  • Amina Azeez

  • Sneha Reji

  • Daya Mani Jacob

  • Mustafa Sarmad Al Hamdani

  • Sondous Eksheir

  • Latifa Nabeel Alsaad

  • Jayakumary Muttappallymyalil

  • Satish Chandrasekhar Nair

  • Jayadevan Sreedharan

  • July 21, 2026

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Objective:

To systematically explore the prevalence of thyroid disorders in coastal and inland regions and understand the impact of dietary, environmental, demographic, and healthcare access differences on thyroid disease occurrence.

Approach:
  • Methodology: Databases such as PubMed, Google Scholar, and Scopus were used to identify articles following PRISMA 2020 guidelines. Twenty-three articles were selected based on specific criteria including language, publication date, and relevance to thyroid disease prevalen…
Key Findings:
  • Higher prevalence of thyroid cancer and thyroid nodules in coastal populations.
  • Goiter and hypothyroidism more prevalent in inland and mountainous areas.
  • Iodine status, seafood consumption, environmental pollutants, iodization of salt, socioeconomic conditions, and healthcare access influenced thyroid disease prevalence.
  • Female gender and older age were significantly associated with a greater burden of disease in both regions.
Interpretation:

Geographical location significantly affects the distribution of thyroid disorders, primarily through iodine intake and exposure to environmental pollutants.

Limitations:
  • Limited number of studies specifically comparing coastal and inland populations.
  • Variability in study methodologies and definitions of thyroid disorders.
Conclusion:

Regular monitoring of environmental pollutants, early detection, universal iodization of salt, and proactive iodine supplementation may reduce the prevalence of thyroid disorders.

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