Associations between adjuvant antibiotic therapy and fistula formation after incision and drainage of anorectal abscesses: results from a retrospective cohort study - Summary - MDSpire
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Associations between adjuvant antibiotic therapy and fistula formation after incision and drainage of anorectal abscesses: results from a retrospective cohort study
To evaluate the effect of adjuvant antibiotic therapy on fistula formation rates following incision and drainage of cryptoglandular anorectal abscesses.
Key Findings:
60.5% of 770 patients received adjuvant antibiotic therapy.
Overall fistula formation rate was 6.8%.
Overall median time to diagnosis was 15.4 weeks.
No significant differences in fistula formation rates or time to diagnosis between antibiotic and non-antibiotic groups.
Fistula formation was associated with abscess location; diabetes was less common in patients who developed fistulas.
Age > 40 years and intersphincteric abscess were positively associated with fistula formation.
Interpretation:
Adjuvant antibiotic therapy does not reduce the risk of fistula formation after incision and drainage of anorectal abscesses.
Limitations:
Retrospective design may introduce bias, including selection bias and confounding factors.
Data not publicly available for independent verification.
Conclusion:
The study suggests that adjuvant antibiotic therapy is not beneficial in preventing fistula formation post-surgery for anorectal abscesses.
