EYP-1901 for Retinal Exudative Diseases - Summary - MDSpire

EYP-1901 for Retinal Exudative Diseases

Updates from the clinical trial program in Wet AMD and DME

  • By

  • Ashkan M. Abbey

  • May 29, 2026

  • 6 min

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Objective:

To evaluate the efficacy and safety of EYP-1901 in treating retinal exudative diseases such as wet age-related macular degeneration (AMD) and diabetic macular edema (DME).

Key Findings:
  • EYP-1901 met primary endpoint in DAVIO 2, showing non-inferiority to aflibercept based on BCVA change.
  • Over 85% of EYP-1901-treated patients had stable or improved vision at six months.
  • In VERONA, EYP-1901 showed extended time to first supplemental treatment compared to aflibercept.
  • EYP-1901 demonstrated early and sustained vision improvements in DME patients.
Interpretation:

Limitations:
  • EYP-1901 is still investigational and not authorized for sale.
  • Long-term safety and efficacy data are pending from ongoing phase 3 trials.
Conclusion:

Original Source(s)

EYP-1901 for Retinal Exudative Diseases

  • by Ashkan M. Abbey

  • May 29, 2026

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