Incidence and independent risk factors for postoperative delirium in ICU patients after cardiopulmonary bypass cardiac surgery: a retrospective cohort study - Summary - MDSpire

Incidence and independent risk factors for postoperative delirium in ICU patients after cardiopulmonary bypass cardiac surgery: a retrospective cohort study

  • By

  • Chunyan Zhang

  • Huan Yu

  • Wei Zhai

  • Lili Zhang

  • Qing Li

  • Yuanyuan Li

  • July 6, 2026

  • 0 min

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Objective:

To investigate the incidence of delirium in ICU patients after extracorporeal circulation cardiac surgery and analyze key influencing factors related to this patient population.

Approach:
  • Study Design: A retrospective cohort study involving 302 patients who underwent extracorporeal circulation cardiac surgery from January 2023 to June 2025.
Key Findings:
  • The incidence of postoperative delirium (POD) was 28.15%.
  • POD group had higher age, APACHE II scores, sedative use, postoperative hypotension rates, and lower albumin levels (all P < 0.05).
  • Longer aortic cross-clamping time, cardiopulmonary bypass time, and mechanical ventilation time were observed in the POD group (all P < 0.05).
  • Independent risk factors identified included older age, longer mechanical ventilation time, longer aortic cross-clamping time, higher APACHE II score, and lower albumin levels.
Interpretation:

ICU nursing records can effectively identify high-risk patients for POD, providing evidence for early warning and risk stratification.

Limitations:
  • The study is retrospective and may be subject to biases inherent in such designs, including selection bias and information bias.
  • The specific medical environment may limit the generalizability of the findings to other settings.
Conclusion:

The study reports a high incidence of POD after cardiac surgery with extracorporeal circulation and identifies several associated risk factors.

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