To provide data on perioperative complications, reflux control, quality of life, and reduction of comorbidities after Fundoplication and Roux-en-Y Gastric Bypass in patients with moderate obesity, highlighting the significance of these findings in the context of existing literature.
Key Findings:
RYGB resulted in less in-hospital morbidity compared to Fundoplication, suggesting a safer surgical option.
RYGB led to more significant weight loss and better control of comorbidities like diabetes and hypertension, indicating its effectiveness.
Limited studies exist comparing Fundoplication and RYGB in patients with moderate obesity, underscoring the need for further research.
Interpretation:
RYGB may offer superior outcomes in managing GERD and obesity-related comorbidities compared to Fundoplication, although further high-quality trials are needed to confirm these findings.
Limitations:
Retrospective design may introduce bias, affecting the reliability of the results.
Limited sample size and lack of randomization may limit the generalizability of the findings.
No clear international recommendations for surgical technique choice in moderate obesity exist due to the lack of high-quality clinical trials.
Conclusion:
RYGB may be preferable for patients with moderate obesity and refractory GERD, but more research is needed to establish definitive guidelines and improve clinical decision-making.
A retrospective database study found a low absolute incidence but higher relative hazard of ischemic optic neuropathy following semaglutide initiation.
