Objective:

To analyze the clinical characteristics of atypical subcutaneous nodule-type paragonimiasis in children and accumulate experience in its diagnosis and treatment.

Approach:

• Study Design: A retrospective analysis was conducted on the clinical data of 3 pediatric cases with atypical subcutaneous nodule-type paragonimiasis.

Key Findings:

• All patients had a clear epidemiological history.
• Significantly elevated peripheral blood eosinophils were observed.
• All patients tested positive for Paragonimus antibodies.
• Oral praziquantel achieved excellent therapeutic effects.
• Surgery served as an adjuvant treatment.

Interpretation:

Paragonimiasis presents with complex and diverse clinical manifestations, and its clinical symptoms and signs lack specificity. Attention should be paid to taking a detailed epidemiological history; elevated eosinophils and positive Paragonimus antibodies are helpful for diagnosis.

Limitations:

• Small sample size of only three pediatric cases.
• Retrospective nature may limit the generalizability of findings.

Conclusion:

Oral praziquantel combined with adjuvant surgical treatment can yield good clinical outcomes.