PRP Treatment in the Clinic - Summary - MDSpire

PRP Treatment in the Clinic

Evidence suggests platelet-rich plasma can enhance nerve growth and improve gland function in patients with dry eye and neuropathic pain.

  • By

  • Rolando Toyos, MD

  • November 1, 2025

  • 9 min

Share

Objective:

To explore the innovative use of platelet-rich plasma (PRP) in enhancing nerve growth and improving gland function in patients with dry eye disease (DED) and neuropathic pain.

Key Findings:
  • PRP contains higher levels of nerve growth factors and anti-inflammatory mediators compared to AS, with a 20-fold increase in NGF.
  • Patients treated with PRP reported significant improvements in dry eye symptoms and pain, with specific metrics to be included.
  • Microneedling PRP into the skin around glands may enhance their function safely, reducing risks associated with direct injections.
Interpretation:

The findings suggest that PRP is a promising therapeutic option for DED and neuropathic pain, potentially offering better outcomes than traditional treatments.

Limitations:
  • The study lacks large-scale clinical trials to validate the findings, which limits the generalizability of results.
  • Long-term effects and optimal treatment protocols for PRP in ophthalmology remain to be established, necessitating further investigation.
Conclusion:

Integrating PRP into ophthalmology could represent a significant advancement in treating dry eye disease and related neuropathic pain, though broader acceptance and further research are needed to confirm efficacy and safety.

Original Source(s)

PRP Treatment in the Clinic

  • by Rolando Toyos, MD

  • November 1, 2025

Related Content

Elevating Ocular Surface Care

The trilayer decellularized basement membrane is used in ocular surgery and in OSD applications, including corneal and conjunctival-related injuries or defects.

Survey: 96% of Optometrists Assess Smoking Status

Survey finds widespread smoking status screening among optometrists in Wales following national training requirements.

Dry Eye Innovations

Himani Goyal, MD, discusses how advances in dry eye treatments have improved ophthalmic practice and outcomes.

  • May 1, 2026

  • 3 min