Clinical efficacy of Jianqiao ancient moxibustion in treating chronic fatigue syndrome: a single-center randomized controlled superiority trial protocol - Summary - MDSpire

Clinical efficacy of Jianqiao ancient moxibustion in treating chronic fatigue syndrome: a single-center randomized controlled superiority trial protocol

  • By

  • Qimiao Hu

  • Bonuo Qi

  • Yingjun Liu

  • Haijuan Zhang

  • Yulin Liu

  • Yuping Yang

  • Chao Wang

  • June 26, 2026

  • 0 min

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Objective:

To compare the clinical efficacy of Jianqiao ancient moxibustion with that of moxa box moxibustion in patients with chronic fatigue syndrome (CFS) exhibiting a spleen–kidney yang deficiency pattern.

Approach:
  • Study Design: A single-center, single-blind randomized controlled superiority trial enrolling 90 eligible patients diagnosed with CFS.
  • Intervention: Participants will be randomly assigned to receive either Jianqiao ancient moxibustion or moxa box moxibustion, with treatments administered three times per week for 4 weeks.
  • Outcome Measures: Primary outcome: Fatigue Scale-14. Secondary outcomes: Spleen–Kidney Yang Deficiency Symptom Scale, Self-Rating Anxiety Scale, Self-Rating Depression Scale, and infrared thermal imaging.
  • Assessment Schedule: Evaluations will occur at baseline, post-intervention at week 4, and during follow-up at week 16.
Key Findings:
  • The study will utilize infrared thermal imaging to assess changes in thermal characteristics related to moxibustion.
Interpretation:

Limitations:
  • Single-center study may limit generalizability.
  • Single-blind design may introduce bias.
Conclusion:

Sources:

Original Source(s)

Clinical efficacy of Jianqiao ancient moxibustion in treating chronic fatigue syndrome: a single-center randomized controlled superiority trial protocol

  • by Qimiao Hu, Bonuo Qi, Yingjun Liu, Haijuan Zhang, Yulin Liu, Yuping Yang, Chao Wang

  • June 26, 2026

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