Revisiting the Ross operation: early results from a new Ross program at a cardiovascular center in South America - Summary - MDSpire

Revisiting the Ross operation: early results from a new Ross program at a cardiovascular center in South America

  • By

  • Santiago Besa

  • Álvaro Torres

  • Pedro Ugarte

  • Cecilia Romero

  • Rodrigo González

  • Pedro Becker

  • Günther Krögh

  • June 15, 2026

  • 0 min

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Objective:

To describe the implementation of a dedicated adult Ross program and evaluate early clinical and hemodynamic outcomes in a high-complexity cardiovascular center in South America.

Approach:
    Key Findings:
    • 29 patients included (13.8% female; age range: 21–61).
    • Main surgical indications: severe aortic stenosis (34.5%), mixed lesions (34.5%), severe aortic regurgitation (27.6%).
    • 86.2% had bicuspid aortic valves.
    • Associated procedures were performed in 24.1% of cases.
    • Median cross-clamp and cardiopulmonary bypass times were 205 and 230 min, respectively.
    • Early complications included perioperative stroke in 3 patients (10.3%).
    • No severe autograft or homograft regurgitation was observed during follow-up.
    Interpretation:

    The implementation of a dedicated Ross program in a high-complexity center is feasible and associated with acceptable early postoperative outcomes, but further studies are needed to assess long-term durability.

    Limitations:
    • Short median follow-up of 295 days.
    • Small sample size of 29 patients.
    • Potential biases in patient selection.
    Conclusion:

    The findings support the feasibility and short-term safety of the Ross procedure; longer follow-up and larger cohorts are needed for durability assessment.

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