Development and validation of a nomogram for predicting recurrence in patients with Meige syndrome after radiofrequency ablation - Summary - MDSpire

Development and validation of a nomogram for predicting recurrence in patients with Meige syndrome after radiofrequency ablation

  • By

  • Xiang Xu

  • Tao Wang

  • Zi Wang

  • July 14, 2026

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Objective:

To develop and internally validate a nomogram for predicting 1-year recurrence after CT-guided facial nerve radiofrequency ablation in Meige syndrome patients.

Approach:
  • Study Design: Retrospective analysis of 119 patients with Meige syndrome who underwent CT-guided facial nerve radiofrequency ablation.
  • Statistical Analysis: Lasso regression and multivariate logistic regression were used to identify independent factors associated with postoperative recurrence.
  • Nomogram Construction: A nomogram was constructed based on identified predictors and validated using bootstrap resampling.
Key Findings:
  • Independent factors influencing recurrence include the Jankovic Rating score (JRS), disease duration, and final temperature.
  • The nomogram achieved an area under the ROC curve (AUC) of 0.932 (95% CI: 0.912–0.958).
  • Calibration curves showed excellent agreement between predicted probabilities and actual observed values.
  • Decision curve analysis indicated a higher net benefit for the nomogram predictive model.
Interpretation:

Limitations:
  • The study is retrospective and may have inherent biases that could affect the results.
  • The sample size may limit the generalizability of the findings.
Conclusion:

The nomogram aids in identifying high-risk postoperative patients and assists in clinical decision-making.

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