To analyze the characteristics, treatment, and outcomes of patients with spontaneous intracerebral abscesses over a 21-year period (2000-2021).
Key Findings:
217 surgeries for intracranial abscesses were performed; 65 were spontaneous cases.
Most abscesses were located in the frontal lobe (38.46%).
Common pathogens included Streptococcus spp. and Staphylococcus spp.
40% of patients experienced neurological sequelae post-treatment.
No significant correlation between antibiotic treatment duration and clinical outcome.
Interpretation:
The study highlights a significant incidence of spontaneous brain abscesses with varied pathogen profiles, emphasizing the need for tailored treatment approaches based on evolving pathogens.
Limitations:
Retrospective design may introduce selection bias and affect data accuracy.
Limited follow-up duration for some patients.
Single-center study may affect generalizability.
Conclusion:
Spontaneous brain abscesses present significant clinical challenges, necessitating ongoing research into pathogen evolution and treatment efficacy.
by Luisa Mona Kraus, Manou Overstijns, Amir El Rahal, Simon Behringer, Klaus-Jürgen Buttler, Lukas Andereggen, Jürgen Beck, Oliver Schnell, Daniel Hornuss, Dirk Wagner, Debora Cipriani
Epilepsy remains a life-altering condition, particularly due to the unpredictable nature of seizures and their cumulative impact on cognition, independence and quality of life.
