Regional Mortality From Chronic Liver Diseases in African Countries Attributable to Hepatitis B Virus and Hepatitis C Virus Infections From 1990 to 2021 and Projections to 2030 - Summary - MDSpire
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Regional Mortality From Chronic Liver Diseases in African Countries Attributable to Hepatitis B Virus and Hepatitis C Virus Infections From 1990 to 2021 and Projections to 2030
To explore the burden and trends of chronic liver diseases (CLD) in Africa due to HBV and HCV, using specific metrics to assess progress towards their elimination by 2030.
Key Findings:
In 2021, CLD-related deaths were higher for HBV (81,074) than HCV (60,717), with data directly supporting these findings.
Western Africa had the highest number of CLD deaths from HBV (33,603) and HCV (19,583), supported by data.
Central Africa exhibited the highest ASDR for both HBV (16.1) and HCV (12.7), with data backing this claim.
Predicted increases in CLD deaths by 2030 include 42.5% for HBV in Eastern Africa and 45.5% for HCV in Central Africa, based on projections.
Despite a decline in ASDR, the overall mortality burden from CLD increased significantly from 1990 to 2021, with data supporting this conclusion.
Interpretation:
Most African regions are unlikely to meet the WHO's 2030 elimination target for CLD due to HBV and HCV, highlighting the need for enhanced international support, with specific examples.
Limitations:
The study is limited by the availability and accuracy of data from the Global Burden of Disease database, which may affect the reliability of findings.
Socioeconomic factors influencing healthcare access were not fully explored, potentially impacting the conclusions drawn.
Conclusion:
The increasing burden of CLD due to HBV and HCV in Africa necessitates urgent action to improve healthcare access and resources to meet global elimination goals.
