Case report: Non-surgical triumph in pericardial paraganglioma: durable tumor regression via targeted embolization of coronary collaterals - Summary - MDSpire

Case report: Non-surgical triumph in pericardial paraganglioma: durable tumor regression via targeted embolization of coronary collaterals

  • By

  • Zaiqiang Zhang

  • Jiawang Ding

  • May 11, 2026

  • 0 min

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Objective:

To demonstrate the effectiveness of transcatheter embolization in managing a pericardial paraganglioma in a patient who declined surgical intervention, emphasizing the case-specific nature of the findings.

Key Findings:
  • Significant tumor regression was observed at the one-year follow-up, indicating the effectiveness of the embolization.
  • Post-procedural urinary catecholamine levels normalized, suggesting successful treatment.
  • The patient reported substantial symptom resolution and maintained controlled blood pressure, underscoring the treatment's impact.
Interpretation:

This case underscores the potential of non-surgical interventions like embolization for treating inoperable pericardial tumors, while also highlighting the importance of multimodal imaging in achieving favorable management outcomes.

Limitations:
  • The study is based on a single case, limiting generalizability and necessitating further research to validate findings.
  • Long-term outcomes beyond one year are not assessed, which may affect the understanding of the treatment's durability.
Conclusion:

Transcatheter embolization can be an effective non-surgical management strategy for pericardial paragangliomas, providing significant symptom relief and tumor reduction.

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