To explore the agreement between µQFR and 3D-QFR for functional assessment of donor vessels in patients with chronic total occlusions (CTO), highlighting its potential clinical significance.
Key Findings:
336 patients were included; 23 donor vessels were unsuitable for 3D-QFR analysis, indicating a need for careful selection in clinical settings.
Mean age of participants was 60.8 years; 81.2% were male, reflecting the demographic profile of CTO patients.
Majority of CTO lesions were located in the LAD (43.2%) and RCA (44.0%), which are critical areas for intervention.
Interpretation:
µQFR may provide a feasible alternative to 3D-QFR for assessing donor vessels in CTO patients, especially when obtaining multiple angiographic projections is challenging, potentially impacting clinical decision-making.
Limitations:
Retrospective design may introduce selection bias, which should be considered when interpreting results.
Limited data on the agreement between µQFR and 3D-QFR specifically for collateral donor vessels, indicating a gap in the literature.
Conclusion:
The study suggests that µQFR could be a viable method for functional assessment of donor vessels in CTO patients, warranting further investigation to validate its clinical utility.