Efficacy and anthropometric predictors of negative-pressure therapy for recurrent concealed penis in pediatric patients - Summary - MDSpire

Efficacy and anthropometric predictors of negative-pressure therapy for recurrent concealed penis in pediatric patients

  • By

  • Shengqi Zheng

  • Bingqian Yin

  • Ruiyun Xue

  • Meng Fu

  • Hong Chen

  • Xu Cui

  • Chaoming Zhou

  • June 18, 2026

  • 0 min

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Objective:

To evaluate the clinical efficacy, safety, and three-month durability of negative-pressure therapy (NPT) as a non-surgical salvage intervention for pediatric patients with postoperative recurrent concealed penis.

Approach:
    Key Findings:
    • Significant morphometric gains were achieved across all dimensions (all P < 0.001).
    • VPL increased by a mean of 0.76 cm (95% CI: 0.68 to 0.84), demonstrating a substantial clinical effect (Cohen's dz = 1.64).
    • Anatomical gains in FPL, SPL, and diameter were maintained at 3 months with no significant regression (P > 0.05).
    • Advanced chronological age, higher body mass index, and smaller baseline dimensions were independent predictors of superior anatomical improvement.
    • The protocol was well tolerated with no serious adverse events.
    Interpretation:

    NPT is an effective, non-invasive salvage strategy for pediatric recurrent concealed penis, providing stable anatomical expansion through mechanotransduction and serving as an alternative to complex re-operation.

    Limitations:
    • Retrospective design may introduce selection bias.
    • Lack of a control group limits comparison of outcomes, potentially affecting the validity of the findings.
    Conclusion:

    NPT offers a viable non-surgical option for managing recurrent concealed penis in children, particularly for those with specific anthropometric characteristics.

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