Current issues in clinical staging of perihilar cholangiocarcinoma—a European snapshot survey - Summary - MDSpire

Current issues in clinical staging of perihilar cholangiocarcinoma—a European snapshot survey

  • By

  • Hannes Jansson

  • Martina Nebbia

  • Barbara M. Zonderhuis

  • Maria Gustafsson-Liljefors

  • Lynn E. Nooijen

  • Aris Grigoriadis

  • Torkel Brismar

  • Rogier P. Voermans

  • Christina Villard

  • Joris I. Erdmann

  • Stefan Gilg

  • June 23, 2026

  • 0 min

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Objective:

To improve understanding of current issues in the clinical staging of perihilar cholangiocarcinoma (pCCA) through a pan-European survey.

Approach:
    Key Findings:
    • 51 clinicians from 47 medical centres across 20 European countries participated.
    • 94% of centres had multidisciplinary team (MDT) conferences for patient assessment.
    • 53% of centres offered evaluation for transplantation eligibility for unresectable pCCA, with significant differences based on centralization.
    • 76% of centres recommended MRI with liver-specific contrast for localized disease assessment.
    • 51% of centres preferred endoscopic biliary drainage as the primary intervention for biliary obstruction.
    Interpretation:

    The survey reveals variability in clinical practices and resources for the staging and management of pCCA across Europe.

    Limitations:
    • The survey was voluntary and may not represent all clinicians involved in pCCA management.
    • Data were collected from a limited number of centres, which may affect generalizability.
    Conclusion:

    The findings indicate challenges and variability in the clinical staging and management of pCCA.

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