Cardiovascular involvement in ankylosing spondylitis and axial spondyloarthritis: epidemiology, mechanisms, and clinical management - Summary - MDSpire

Cardiovascular involvement in ankylosing spondylitis and axial spondyloarthritis: epidemiology, mechanisms, and clinical management

  • By

  • Xiaoxi Dai

  • Qi Zhao

  • May 18, 2026

  • 0 min

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Objective:

This review emphasizes the significance of cardiovascular implications in ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA), highlighting the increased risk of cardiovascular disease in these patients.

Key Findings:
  • The review found that the prevalence rates of subclinical abnormalities, such as left ventricular hypertrophy and increased arterial stiffness, are notably higher in patients with AS/axSpA compared to the general population.
Interpretation:

There is a critical need for integrated management strategies that address both musculoskeletal and cardiovascular health in patients with AS and axSpA.

Limitations:
  • The review's comprehensiveness may be impacted by language restrictions, limiting the inclusion of relevant studies published in non-English languages.
Conclusion:

Ongoing research into the cardiovascular implications of AS and axSpA is essential to improve patient outcomes and inform clinical practice.

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