To evaluate the outcomes of DAIR-Plus and partial two-stage exchange in chronic knee megaprosthetic infections and identify prognostic factors for treatment suitability, emphasizing the significance of these factors.
Key Findings:
DAIR-Plus and PTSE showed variable success rates in resolving chronic PJIs, with specific rates to be included.
Patient characteristics and preoperative imaging influenced the choice of surgical technique.
Infection resolution was measured through clinical signs and laboratory tests over a minimum follow-up of two years.
Interpretation:
The study suggests that DAIR-Plus may be a viable option for select chronic knee megaprosthesis infections, potentially avoiding more invasive procedures, with implications for patient management.
Limitations:
Small sample size may limit generalizability of results.
Retrospective design may introduce bias in patient selection and outcome assessment, which should be explicitly stated.
Lack of clarity in defining treatment protocols and outcomes across existing literature.
Conclusion:
DAIR-Plus and PTSE can be effective for chronic PJIs in knee megaprostheses, but careful patient selection and further studies are needed to optimize treatment strategies and validate findings.
