Late Preterm Steroids: No Lung Benefit - Summary - MDSpire
From the Journals

Late Preterm Steroids: No Lung Benefit

Follow-up of the ALPS trial found similar rates of respiratory impairment at age 6 years or older with betamethasone vs placebo

  • By

  • Andrea Surnit

  • May 12, 2026

  • 5 min

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A follow-up study from the ALPS trial found no significant difference in childhood respiratory impairment between children exposed to antenatal betamethasone and those exposed to placebo. Among 1,218 participants aged 6 or older, the rate of respiratory issues was similar in both groups at 35% for betamethasone and 36% for placebo. While short-term benefits of betamethasone during late preterm delivery are established, this study suggests that it does not improve long-term pulmonary outcomes in children, highlighting the influence of late preterm birth itself on respiratory health.

Original Source(s)

Late Preterm Steroids: No Lung Benefit

  • by Andrea Surnit

  • May 12, 2026

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