Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score - Summary - MDSpire

Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score

  • By

  • Yeun-Yoon Kim

  • Won Chang

  • Jeong Min Lee

  • Se Woo Kim

  • Jae Seok Bae

  • Jeongin Yoo

  • Sun Kyung Jeon

  • HeeSoo Kim

  • Young Hoon Kim

  • Jin-Young Choi

  • Eun Ju Cho

  • Yun Bin Lee

  • Sook-Hyang Jeong

  • Do Young Kim

  • Yunhee Choi

  • Jeong Hee Yoon

  • October 25, 2025

  • 0 min

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Objective:

To develop and validate a model predicting HCC risk using ultrasound features in patients with viral hepatitis who are eligible for intensive HCC surveillance.

Key Findings:
  • Ultrasound features significantly correlated with HCC risk, indicating their potential utility in clinical settings.
  • The SELECT score effectively stratified patients into low, intermediate, and high-risk groups, facilitating targeted surveillance.
  • The model demonstrated better predictive capability compared to existing HCC risk scoring systems, suggesting its superiority.
Interpretation:

The SELECT score provides a practical tool for identifying patients at high risk for HCC, enabling targeted surveillance strategies.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the generalizability of the findings.
  • Findings may not be generalizable to populations outside the study settings, limiting broader applicability.
Conclusion:

The SELECT score enhances risk stratification for HCC in patients with viral hepatitis, supporting more effective surveillance practices and improving patient outcomes.

Original Source(s)

Hepatocellular carcinoma risk stratification to identify patients suitable for intensive surveillance in viral hepatitis: the SELECT score

  • by Yeun-Yoon Kim, Won Chang, Jeong Min Lee, Se Woo Kim, Jae Seok Bae, Jeongin Yoo, Sun Kyung Jeon, HeeSoo Kim, Young Hoon Kim, Jin-Young Choi, Eun Ju Cho, Yun Bin Lee, Sook-Hyang Jeong, Do Young Kim, Yunhee Choi, Jeong Hee Yoon

  • October 25, 2025

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