CT-derived extracellular volume fraction as a predictive marker for postoperative recurrence in pStage II–III gastric cancer - Summary - MDSpire

CT-derived extracellular volume fraction as a predictive marker for postoperative recurrence in pStage II–III gastric cancer

  • By

  • Yusuke Nishimuta

  • Daisuke Tsurumaru

  • Nobuhiro Fujita

  • Satohiro Kai

  • Junki Maehara

  • Yasuhiro Ushijima

  • Eiji Oki

  • Kousei Ishigami

  • June 18, 2025

  • 0 min

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Objective:

To explore the relationship between preoperative CT-derived extracellular volume fraction (CT-ECV) and recurrence risk in patients with pathological stage II–III gastric cancer following curative gastrectomy, highlighting its potential as a novel prognostic marker.

Key Findings:
  • Preoperative CT-ECV values were found to correlate with the extracellular stroma in gastric cancer, with a correlation coefficient of X (insert actual value).
  • Patients with higher CT-ECV values had a higher risk of postoperative recurrence, with a hazard ratio of Y (insert actual value).
Interpretation:

CT-derived ECV may serve as a valuable imaging biomarker for predicting recurrence in stage II–III gastric cancer, potentially aiding in preoperative treatment planning.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the generalizability of the results.
  • Limited generalizability due to single-center study, suggesting the need for multicenter validation.
Conclusion:

CT-ECV is a promising predictive marker for postoperative recurrence in gastric cancer, warranting further investigation in larger, multicenter studies to validate its clinical utility.

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