Hemodynamic profile of neonatal fungal sepsis with insights into the disease spectrum: a retrospective study - Summary - MDSpire
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Cardiovascular Characteristics of Neonatal Fungal Sepsis: A Retrospective Analysis of Clinical Variability

  • By

  • Arshdeep Kaur

  • Priyadarshini Virupaxi Chougula

  • Nandini Malshe

  • Pari Singh

  • Pradeep Suryawanshi

  • August 21, 2026

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Objective:

To assess the clinical spectrum of neonatal fungal sepsis with a focus on cardiovascular alterations evaluated by functional echocardiography.

Approach:
  • Study Design: Retrospective observational study conducted over three years in a tertiary care neonatal intensive care unit.
  • Inclusion Criteria: Neonates younger than 28 days with culture-proven fungal sepsis.
  • Data Collection: Demographic, clinical, microbiological, and outcome variables were analyzed from electronic medical records.
  • Echocardiography Protocol: Functional echocardiography was performed during active infection and repeated after microbiological clearance.
Key Findings:
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Interpretation:

Neonatal fungal sepsis is associated with reversible hemodynamic changes, particularly affecting right ventricular performance and pulmonary circulation.

Limitations:
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Conclusion:

Functional echocardiography may provide useful physiological information for managing neonatal fungal sepsis.

Sources:

Original Source(s)

Hemodynamic profile of neonatal fungal sepsis with insights into the disease spectrum: a retrospective study

  • by Arshdeep Kaur, Priyadarshini Virupaxi Chougula, Nandini Malshe, Pari Singh, Pradeep Suryawanshi

  • August 21, 2026

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