To compare cognitive performance and well-being in older adults with different self-reported levels of subjective energy and explore potential phenotypic heterogeneity.
Approach:
Study Design: Cross-sectional study on older adults from the general population.
Participant Classification: Participants classified as having higher versus lower levels of perceived energy based on the SF-12 questionnaire.
Cognitive Assessment: Cognitive performance assessed using the Addenbrooke’s Cognitive Examination-Revised (ACE-R).
Additional Evaluations: Depressive symptoms evaluated with the PHQ-9, biological and behavioral rhythm regulation with the BRIAN, and quality of life with the SF-12.
Key Findings:
Significant difference in global cognitive performance between higher and lower perceived energy groups (p=0.012).
Higher perceived energy group showed lower scores in language (p=0.011) and attention/orientation (p=0.049).
Higher perceived energy group reported fewer depressive symptoms (p=0.013), better social and behavioral rhythm regulation (p=0.005), and higher quality of life (p<0.001).
Interpretation:
Hyperenergy in older adults with preserved well-being is not associated with global cognitive impairment.
Limitations:
Cross-sectional design limits causal inferences.
Further longitudinal studies are needed to clarify clinical and cognitive implications.
Conclusion:
The findings indicate a high-energy profile characterized by preserved or enhanced functioning and overall well-being.
Poorer dermatology-related quality of life was associated with greater mental health issues, while habitual probiotic intake showed no measurable relationship with these outcomes.
