To develop a real-time monitoring tool for viral particles in vaccine manufacturing using Raman spectroscopy.
Key Findings:
The Raman spectroscopy-based tool allows for real-time monitoring of viral particles in less than 30 seconds.
The tool can be integrated into continuous manufacturing processes, improving quality control.
Early detection of defects can save time and money while enhancing product yield and quality.
Interpretation:
The development of this tool represents a significant advancement in vaccine manufacturing, enabling rapid quality control and process adjustments.
Limitations:
Challenges remain in improving the limit of detection during early production stages.
Complex media may affect the accuracy of the Raman spectroscopy measurements.
Conclusion:
The integration of portable Raman systems into commercial manufacturing lines could revolutionize the monitoring of viral particles in vaccine production.
