Symptomatic stratification based on morphological features of carotid WEB (SCORE-WEB) - Summary - MDSpire

Symptomatic stratification based on morphological features of carotid WEB (SCORE-WEB)

  • By

  • Batista, Sávio

  • Damiani Monteiro, Mateus

  • Nahab, Fadi

  • Nascimento Martins, Pedro

  • Dolia, Jaydevsinh N

  • Yelam, Theja

  • Frankel, Michael

  • Oshinski, John

  • Mohamed, Ghada A

  • Allen, Jason

  • Haussen, Diogo C

  • April 9, 2026

  • 0 min

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Objective:

To develop a functional risk score (SCORE-WEB) for categorizing symptomatic and asymptomatic carotid webs (CaW) based on morphological characteristics.

Key Findings:
  • 126 CaW cases evaluated: 80 symptomatic and 46 asymptomatic.
  • Symptomatic lesions had more acute pre-web angles, larger pocket areas, and greater distal cervical internal carotid and bulb calibers.
  • SCORE-WEB achieved an AUC of 0.824 with an optimal cutoff of ≥7 points.
Interpretation:

Distinct morphological characteristics significantly influence the symptomatic status of CaW, and the SCORE-WEB shows promise for clinical application.

Limitations:
  • Results require validation in larger and prospective datasets.
  • The role of clinical variables in enhancing predictive performance needs further exploration.
Conclusion:

The SCORE-WEB, based on five anatomical parameters, demonstrates good discrimination for symptomatic CaW and may have practical utility in clinical settings.

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