Development and validation of a nomogram model for predicting the risk of failed manual reduction in distal radius fractures - Summary - MDSpire

Development and validation of a nomogram model for predicting the risk of failed manual reduction in distal radius fractures

  • By

  • Mingyue Fan

  • Binbin Gu

  • June 11, 2026

  • 0 min

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Objective:

To develop a nomogram model for predicting the risk of failed manual reduction in patients with distal radius fractures (DRF) and to validate its predictive performance.

Approach:
    Key Findings:
    • Eight independent risk factors were identified: AO classification, severity of swelling, etiology of the fracture, time from injury to reduction, pre-reduction palmar tilt angle, radial shortening height, pre-reduction ulnar deviation angle, and history of alcohol consumption.
    • The receiver operating characteristic curve showed an area under the curve (AUC) of 0.878 (95% CI: 0.855–0.901), with a sensitivity of 75.4% and a specificity of 82.5%.
    • The calibration curve demonstrated good agreement between predicted and observed probabilities, with a mean absolute error of 0.005 after bootstrap internal validation (1,000 iterations).
    Interpretation:

    Limitations:
    • The study was retrospective and conducted at a single institution.
    • Osteoporosis was defined based on limited criteria, which may affect classification accuracy.
    Conclusion:

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