Clinical Evaluation of the Peripheral Perfusion Index as a Predictor of Femoral Nerve Block Efficacy in Unilateral Arthroscopic Meniscal Surgery - Summary - MDSpire

Clinical Evaluation of the Peripheral Perfusion Index as a Predictor of Femoral Nerve Block Efficacy in Unilateral Arthroscopic Meniscal Surgery

  • By

  • Gong, yao

  • Zhang, li

  • He, qi

  • Wei, Wei

  • Zhang, cuo mao ji

  • April 30, 2026

  • 0 min

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Objective:

To investigate the potential of Perfusion index (PI) as a reliable indicator for assessing the efficacy of femoral nerve block (FNB) in patients undergoing unilateral arthroscopic meniscal surgery.

Key Findings:
  • The area under the ROC curve (AUROC) of the PI value at T6 on the blocked side was 0.993 (95% CI: 0.982-1.000).
  • Sensitivity was 96.7% and specificity was 93.3% with a cut-off value of 1.755 and a Youden index of 0.934.
  • PI values differed significantly between the blocked and non-blocked sides at all time points (P<0.001).
  • On the blocked side, PI values increased significantly over time, peaking at T6 (mean=2.83±0.72, 2.16 times the baseline).
  • Male PI values on the blocked side increased more than female values (P<0.001).
Interpretation:

The PI represents a sensitive and straightforward method for assessing the success of early FNB, with a value above 1.755 indicating a successful block, which allows anesthesiologists to promptly adjust anesthetic protocols.

Limitations:
  • Potential limitations include the study's single-center design and the lack of long-term follow-up data.
Conclusion:

The findings suggest that monitoring PI can help anesthesiologists adjust anesthetic protocols and enhance the efficiency of knee arthroscopic procedures, aligning with the principles of Enhanced Recovery After Surgery (ERAS).

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