To evaluate the diagnostic value of multimodal ultrasound imaging in triple-negative breast cancer (TNBC).
Key Findings:
Microcalcification, stiff rim sign, lesion shape, posterior attenuation, maximum elastic modulus, and vascular index were identified as independent predictors of TNBC.
The nomogram demonstrated an area under the curve of 0.965, sensitivity of 0.849, and specificity of 0.966.
The optimal diagnostic threshold for the nomogram in predicting TNBC was 0.798.
Interpretation:
Multimodal ultrasound imaging is a highly effective diagnostic tool for preoperative identification of TNBC, potentially improving clinical decision-making.
Limitations:
The study is retrospective, which may introduce selection bias.
The sample size, while substantial, may not be representative of all populations.
The reliance on imaging techniques may overlook other diagnostic factors.
Conclusion:
Multimodal ultrasound imaging offers a promising approach for the early and accurate diagnosis of TNBC, aiding in treatment planning.
