Persistently increased frequency of diabetic ketoacidosis in new-onset type 1 diabetes in Polish children: nationwide analysis 2019–2022 - Summary - MDSpire

Persistently increased frequency of diabetic ketoacidosis in new-onset type 1 diabetes in Polish children: nationwide analysis 2019–2022

  • By

  • Arkadiusz Michalak

  • Barbara Pernak

  • Jędrzej Chrzanowski

  • Iwona Pietrzak

  • Iwona Beń-Skowronek

  • Artur Bossowski

  • Agata Chobot

  • Maria Bednarska

  • Katarzyna Dżygało

  • Wojciech Fendler

  • Barbara Głowińska-Olszewska

  • Martyna Górnicka de Almeida

  • Anita Horodnicka-Józwa

  • Katarzyna Jakubek-Kipa

  • Przemysława Jarosz-Chobot

  • Anna Kącka

  • Katarzyna Marcinkiewicz

  • Artur Mazur

  • Małgorzata Myśliwiec

  • Joanna Nazim

  • Barbara Wasyl-Nawrot

  • Elżbieta Niechciał

  • Anna Noczyńska

  • Ewa Rusak

  • Sebastian Seget

  • Monika Seifert

  • Elżbieta Skotarczyk-Kowalska

  • Anna Skowronek

  • Lidia Groele

  • Paulina Wais

  • Mieczysław Walczak

  • Anna Wołoszyn-Durkiewicz

  • Marta Wysocka-Mincewicz

  • Agnieszka Zubkiewicz-Kucharska

  • Agnieszka Szadkowska

  • June 29, 2026

  • 0 min

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Objective:

To assess the frequency and severity of diabetic ketoacidosis (DKA) in Polish children with new-onset type 1 diabetes (T1D) from 2019 to 2022.

Approach:
  • Study Design: A multicenter national retrospective study analyzing new-onset T1D cases in Polish children diagnosed from January 2019 to December 2022.
  • Data Collection: Anonymized data was collected from pediatric diabetes centers across Poland, focusing on clinical presentation and DKA diagnosis criteria.
  • Inclusion Criteria: Included children aged <18 years with T1D diagnosed based on symptoms and blood glucose levels.
  • Exclusion Criteria: Excluded cases diagnosed by other criteria, different diabetes types, and missing essential data.
Key Findings:
  • 54.5% of children presented with DKA at diagnosis.
  • DKA frequency increased from 47.9% in 2019 to 58.6% in 2020 (p<0.0001) and decreased to 54.0% in 2022.
  • Observed DKA during the pandemic (56.8%) exceeded model predictions (47.5%; p=0.0041).
  • Children were more likely to present with moderate or severe DKA during the pandemic.
Interpretation:

The study indicates a significant increase in DKA incidence and severity during the pandemic, highlighting the need for improved awareness of diabetes symptoms.

Limitations:
  • Data on ketone assessment was not consistently recorded, leading to potential underreporting of DKA cases.
  • The retrospective study design may introduce biases.
Conclusion:

The findings reveal an increase in DKA incidence among newly diagnosed T1D children during the pandemic.

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