Initial evidence of effects of a novel digital behavioural treatment for chronic pain: A series of replicated randomized single-case experimental design studies - Summary - MDSpire

Initial evidence of effects of a novel digital behavioural treatment for chronic pain: A series of replicated randomized single-case experimental design studies

  • By

  • Haya Al Sharaa

  • Sara Laureen Bartels

  • Patrick Onghena

  • Afra Taygar

  • Linnéa Engman

  • Ida Flink

  • Suzanne Petersson

  • Katja Boersma

  • Lance M. McCracken

  • Laura Simons

  • Johan W.S. Vlaeyen

  • Rikard K. Wicksell

  • July 14, 2026

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Objective:

To provide initial evidence of effects of a newly developed digital behavioral treatment for chronic pain and to assess day-to-day changes in psychological flexibility, acceptance, pain-related functioning, pain intensity, and well-being.

Approach:
  • Study Design: A replicated randomized multiple-baseline single-case experimental design (SCED) was utilized, incorporating pre- and post-treatment assessments and digital diary data.
  • Participants: Participants included individuals aged 18 or older with chronic pain for at least three months, fluent in Swedish, and with access to digital devices.
Key Findings:
  • The study utilized daily diary methods to capture fluctuations in psychological processes and pain-related outcomes.
  • Initial evidence suggests potential benefits of the digital behavioral treatment for chronic pain, particularly in enhancing psychological flexibility and acceptance.
  • The SCED approach allows for individual-level treatment effects to be assessed in a heterogeneous sample.
Interpretation:

The findings indicate that daily assessments may be sensitive to changes in psychological flexibility and acceptance during digital behavioral treatment, as observed in the study.

Limitations:
  • The study's sample was heterogeneous, which may affect the generalizability of the findings.
  • The optimization phase involved small cohorts, which may limit the robustness of the results and the confidence in the findings.
Conclusion:

The study aims to inform the design of a larger clinical trial with a randomized controlled design.

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