Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases - Summary - MDSpire

Case Report: Indocyanine green fluorescence imaging in complex focal nodular hyperplasia resection: report of two cases

  • By

  • Fangkai Du

  • Xie Song

  • Wentao Wang

  • Huizhong Shi

  • Zhengjian Wang

  • Chaoqun Ma

  • Qingqiang Ni

  • Shunzhen Zheng

  • Hong Chang

  • June 15, 2026

  • 0 min

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Objective:

To describe the use of indocyanine green (ICG) fluorescence guidance combined with intraoperative ultrasonography (IOUS) for laparoscopic parenchyma-sparing excision of selected perivascular focal nodular hyperplasia (FNH).

Approach:
    Key Findings:
    • Both patients underwent successful wedge excision with negative surgical margins.
    • Estimated blood loss was 50 mL and 20 mL for the two cases, respectively.
    • Incidental punctate hyperfluorescent foci were observed; one showed benign hyperplastic changes on histology.
    Interpretation:

    Remove unsupported conclusions about clinical value.

    Limitations:
    • The absence of hepatobiliary phase MRI before surgery limited preoperative diagnostic workup in Case 1.
    • The clinical significance of incidental hyperfluorescent foci remains uncertain.
    Conclusion:

    Revise to reflect only the findings stated in the source without implications.

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