Uncommon Presentation of Onychomycosis Caused by Aspergillus niger in a Healthy Adult: A Case of Non-Dermatophyte Mold Infection - Summary - MDSpire

Uncommon Presentation of Onychomycosis Caused by Aspergillus niger in a Healthy Adult: A Case of Non-Dermatophyte Mold Infection

  • By

  • Sugat A. Jawade

  • Nandkishor J. Bankar

  • Sudhir P. Singh

  • Sabiha T. Quazi

  • Mayur S. Dudhe

  • Rutwik Khandeshe

  • January 22, 2026

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Objective:

To highlight a rare case of onychomycosis caused by Aspergillus niger in an immunocompetent adult and emphasize the need for accurate diagnosis of non-dermatophyte mold infections, particularly in the context of rising NDM prevalence.

Approach:
    Key Findings:
    • Onychomycosis can be caused by non-dermatophyte molds like Aspergillus niger, even in healthy individuals.
    • NDM infections often present with atypical features, complicating diagnosis.
    • Accurate diagnosis requires clinical suspicion and confirmatory mycological investigations, including histopathological examination.
    Interpretation:

    The case underscores the evolving understanding of NDMs as primary pathogens in onychomycosis, necessitating increased awareness among clinicians for timely diagnosis and treatment.

    Limitations:
    • Histopathological examination was not performed, which could have confirmed fungal invasion and is crucial for accurate diagnosis.
    Conclusion:

    This case illustrates the importance of recognizing non-dermatophyte molds in onychomycosis and highlights the successful treatment of such infections.

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