AI-driven early infectious disease detection in Dutch primary care using BERT and ERNIE - Summary - MDSpire

AI-driven early infectious disease detection in Dutch primary care using BERT and ERNIE

  • By

  • Maarten Homburg

  • Gijs Danoe

  • Marjolein Y. Berger

  • Tim olde Hartman

  • Jean Muris

  • Andreas Voss

  • Axel Hamprecht

  • Maarten F. Brilman

  • Lilian L. Peters

  • Matthijs S. Berends

  • December 23, 2025

  • 0 min

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Objective:

To develop and validate ERNIE, an AI-driven framework for early detection of infectious diseases using unstructured primary care data.

Key Findings:
  • ERNIE detected COVID-19-like clusters before the first confirmed case.
  • It identified RSV patterns during the 2021 surge and flagged simulated West Nile Virus cases.
  • The framework achieved a consultation-level recall of 0.97, cluster precision of 0.82, and cluster recall of 0.90.
Interpretation:

ERNIE enables early and interpretable detection of emerging health threats using routine clinical text, enhancing surveillance capabilities without reliance on diagnostic codes or laboratory confirmation.

Limitations:
  • The study's findings are based on data from a specific region, which may limit generalizability.
  • The reliance on unstructured text data may introduce variability in data quality and interpretation.
Conclusion:

ERNIE represents a significant advancement in AI-driven surveillance for infectious diseases, with potential applications in various health domains.

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